SERPINA12 Protein (AA 21-414) (DYKDDDDK Tag)
Quick Overview for SERPINA12 Protein (AA 21-414) (DYKDDDDK Tag) (ABIN2746005)
Target
See all SERPINA12 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 21-414
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Purification tag / Conjugate
- This SERPINA12 protein is labelled with DYKDDDDK Tag.
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Purpose
- Vaspin (human) (rec.)
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Cross-Reactivity
- Human
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Characteristics
- Human vaspin (aa 21-414) is fused at the N-terminus to a FLAG®-tag.
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Endotoxin Level
- <0.01EU/μg purified protein (LAL test).
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with 100 μL sterile water.
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Concentration
- 0.1 mg/mL
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Buffer
- Contains PBS.
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Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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Expiry Date
- 6 months
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- SERPINA12 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12 (SERPINA12))
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Alternative Name
- Vaspin
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Background
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Visceral Adipose Tissue-derived Serine Protease Inhibitor, Serpin A12, OL-64
Vaspin (Visceral adipose tissue-derived serpin, Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and was found to be correlated with various metabolic parameters. Vaspin may represent a novel biomarker for obesity and impaired insulin sensitivity and might serve as a new therapeutic target of metabolic syndrome.
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Molecular Weight
- ~55kDa (SDS-PAGE)
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UniProt
- Q8IW75
Target
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