CX3CL1 Protein
Quick Overview for CX3CL1 Protein (ABIN2830149)
Target
See all CX3CL1 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Sequence
- QHLGMTKCEI MCGKMTSRIP VALLIRYQLN QESCGKRAIV LETTQHRRFC ADPKEKWVQD AMKHLDHQAA ALTKNG
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Characteristics
- Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human peripheral blood lymphocytes (PBL) is less than 0.5 μg/mL, corresponding to a specific activity of > 2000 IU/mg.
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Sterility
- 0.2 μm filtered
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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- CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
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Alternative Name
- Cx3cl1
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Background
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Relevance: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium (By similarity). Binds to CX3CR1. {ECO:0000250}.
Synonyms: C-X3-C motif chemokine 1, Neurotactin, Small-inducible cytokine D1, , -
Molecular Weight
- 8.7 kDa
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UniProt
- O35188
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Pathways
- Synaptic Membrane
Target
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