SOD2 Protein (AA 1-222) (His tag)
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- Target See all SOD2 Proteins
- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-222
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SOD2 protein is labelled with His tag.
- Purpose
- Recombinant Human SOD2/Mn-SOD (N-6His)
- Sequence
- MHHHHHHDDD DKKHSLPDLP YDYGALEPHI NAQIMQLHHS KHHAAYVNNL NVTEEKYQEA LAKGDVTAQI ALQPALKFNG GGHINHSIFW TNLSPNGGGE PKGELLEAIK RDFGSFDKFK EKLTAASVGV QGSGWGWLGF NKERGHLQIA ACPNQDPLQG TTGLIPLLGI DVWEHAYYLQ YKNVRPDYLK AIWNVINWEN VTERYMACKK
- Characteristics
- Recombinant Human Superoxide Dismutase [Mn] Mitochondrial/SOD2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Lys222) of Human SOD2 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product SOD2 Protein
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Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 1-222) protein (GST tag)
SOD2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 1-222) protein (His tag)SOD2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 1-140) protein (GST tag)SOD2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,100 mM NaCl,50 % glycerol, pH 8.0.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
- Alternative Name
- SOD2 (SOD2 Products)
- Sub Type
- Fusionprotein
- Background
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Superoxide Dismutase (SOD2) is a number of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. The SOD2 protein transforms toxic superoxide and a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. Genetic variation in SOD2 is associated with microvascular complications of diabetes type 6 (MVCD6), idiopathic cardiomyopathy (IDC), sporadic motor neuron disease, and cancer. SOD2 destroys superoxide anion radicals which are usually produced within the cells and which are toxic to biological systems.
Alternative Names: Superoxide Dismutase [Mn] Mitochondrial, SOD2 - Molecular Weight
- 23.7 kDa
- UniProt
- P04179
- Pathways
- Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling
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