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SOD2 Protein (His tag)

SOD2 Origin: Human Host: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319047
  • Target See all SOD2 Proteins
    SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
    Protein Type
    Recombinant
    Origin
    • 12
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 20
    • 13
    • 3
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This SOD2 protein is labelled with His tag.
    Purpose
    Recombinant Human SOD2/Mn-SOD Protein (His Tag, Human Cells)
    Sequence
    Lys25-Lys222
    Characteristics
    Recombinant Human Superoxide Dismutase [Mn] Mitochondrial is produced by our Mammalian expression system and the target gene encoding Lys25-Lys222 is expressed with a 6His tag at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product SOD2 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
    Alternative Name
    SOD2/Mn-SOD (SOD2 Products)
    Synonyms
    LOC100101896 Protein, MNSOD Protein, GB14346 Protein, sod2 Protein, MGC88869 Protein, Sod2 Protein, CG8905 Protein, Dmel\\CG8905 Protein, Mito SOD Protein, Mn SOD Protein, Mn-SOD Protein, Mn-SOD2 Protein, MnSOD Protein, MnSODII Protein, Mn[2+]SOD Protein, SOD Protein, SOD-2 Protein, SOD2 Protein, Sod-2 Protein, dSOD2 Protein, mitSOD2 Protein, mnSOD Protein, IPOB Protein, MVCD6 Protein, cb463 Protein, wu:fj33b01 Protein, zgc:73051 Protein, MnSOD Protein, manganese superoxide dismutase Protein, superoxide dismutase 2, mitochondrial Protein, superoxide dismutase 2 Protein, Mn superoxide dismutase Protein, Superoxide dismutase 2 (Mn) Protein, superoxide dismutase 2 L homeolog Protein, BDBG_07234 Protein, LOC100101896 Protein, MNSOD Protein, Sod2 Protein, sod2 Protein, LbMnSOD4 Protein, SOD2 Protein, LOC100282741 Protein, SOD-2 Protein, sod2.L Protein
    Background

    Background: Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide, a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer, while SOD2 is one of the primary enzymes that directly convert potential harmful oxidizing species to harmless metabolites.

    Synonym: Superoxide Dismutase [Mn] Mitochondrial, SOD2

    Molecular Weight
    23.2 kDa
    UniProt
    P04179
    Pathways
    Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling
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