TNFRSF13C Protein (AA 10-71) (Fc Tag)
Quick Overview for TNFRSF13C Protein (AA 10-71) (Fc Tag) (ABIN5526590)
Target
See all TNFRSF13C ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 10-71
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Purification tag / Conjugate
- This TNFRSF13C protein is labelled with Fc Tag.
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Sequence
- AA 10-71
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Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 33.3 kDa. As a result of glycosylation, the protein migrates as 40-45 kDa under reducing (R) condition, and 80-100 kDa under non-reducing (NR) condition (SDS-PAGE).
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Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-71) protein (His tag)
TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-71) protein (His-Avi Tag,Biotin)TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-71) protein (Fc Tag)TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-71) protein (mFc Tag)TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 1-175) protein (His tag)custom-made TNFRSF13C Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 1-184) protein (His tag)custom-made TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (Active) proteinTNFRSF13C Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 10-71) protein (Fc Tag)TNFRSF13C Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-71) protein (His tag)TNFRSF13C Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-76) (Active) protein (His tag)TNFRSF13C Origin: Cynomolgus Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
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Handling Advice
- Please avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
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Alternative Name
- BAFFR
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Background
- BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
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Molecular Weight
- 33.3 kDa
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NCBI Accession
- NP_082351
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Pathways
- NF-kappaB Signaling
Target
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