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Annexin V Protein (FITC,GST tag)

Recombinant Annexin V protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN5564291

Quick Overview for Annexin V Protein (FITC,GST tag) (ABIN5564291)

Target

See all Annexin V (ANXA5) Proteins
Annexin V (ANXA5) (Annexin A5 (ANXA5))

Protein Type

Recombinant

Origin

  • 20
  • 4
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 27
  • 8
  • 2
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS), Flow Cytometry (FACS)

Purity

>95 % (SDS-PAGE)
  • Purification tag / Conjugate

    This Annexin V protein is labelled with FITC,GST tag.

    Purpose

    Annexin V (human) (rec.) (FITC)

    Specificity

    Binds to phosphatidylserine (PS).

    Cross-Reactivity

    Human

    Characteristics

    Recombinant human annexin V fused to a GST-tag.
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    In PBS, pH 7.4, containing 0.02 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Do not freeze. Protect from light.

    Storage

    4 °C

    Storage Comment

    Short Term Storage: +4°C

    Long Term Storage: +4°C

    Use & Stability: Stable for at least 1 year after receipt when stored at +4°C.

    Expiry Date

    12 months
  • Target

    Annexin V (ANXA5) (Annexin A5 (ANXA5))

    Alternative Name

    Annexin V

    Background

    Annexin A5, Endonexin II, Lipocortin V, Placental Anticoagulant Protein I, Calphobindin I, Vascular Anticoagulant-alpha

    Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.

    Molecular Weight

    ~52kDa (SDS-PAGE)

    UniProt

    P08758

    Pathways

    Apoptosis
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