Iba1 Protein (AA 2-147, partial) (His-SUMO Tag)

Catalog No. ABIN5709019

This Recombinant Iba1 protein is produced in Escherichia coli (E. coli).

Quick Overview for Iba1 Protein (AA 2-147, partial) (His-SUMO Tag) (ABIN5709019)

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 %

Product Details

Protein Characteristics: partial, AA 2-147

Purification tag / Conjugate: This Iba1 protein is labelled with His-SUMO Tag.

Sequence: SQTRDLQGGK AFGLLKAQQE ERLDEINKQF LDDPKYSSDE DLPSKLEGFK EKYMEFDLNG NGDIDIMSLK RMLEKLGVPK THLELKKLIG EVSSGSGETF SYPDFLRMML GKRSAILKMI LMYEEKAREK EKPTGPPAKK AISELP

Purification: SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Alternative Name: AIF1

Background: Actin-binding protein that enhances mbrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Molecular Weight: 32.6 kDa

UniProt: P55008

Pathways: Smooth Muscle Cell Migration