Caspase 2 Protein (AA 2-452) (His-SUMO Tag)

Catalog No. ABIN5709201

This Recombinant Caspase 2 protein is expressed in Escherichia coli (E. coli).

Quick Overview for Caspase 2 Protein (AA 2-452) (His-SUMO Tag) (ABIN5709201)

Target: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 %

Product Details

Protein Characteristics: AA 2-452

Purification tag / Conjugate: This Caspase 2 protein is labelled with His-SUMO Tag.

Sequence: AAPSAGSWST FQHKELMAAD RGRRILGVCG MHPHHQETLK KNRVVLAKQL LLSELLEHLL EKDIITLEMR ELIQAKVGSF SQNVELLNLL PKRGPQAFDA FCEALRETKQ GHLEDMLLTT LSGLQHVLPP LSCDYDLSLP FPVCESCPLY KKLRLSTDTV EHSLDNKDGP LCLQVKPCTP EFYQTHFQLA YRLQSRPRGL ALVLSNVHFT GEKELEFRSG GDVDHSTLVT LFKLLGYDVH VLCDQTAQEM QEKLQNFAQL PAHRVTDSCI VALLSHGVEG AIYGVDGKLL QLQEVFQLFD NANCPSLQNK PKMFFIQACR GDETDRGVDQ QDGKNHAGSP GCEESDAGKE KLPKMRLPTR SDMICGYACL KGTAAMRNTK RGSWYIEALA QVFSERACDM HVADMLVKVN ALIKDREGYA PGTEFHRCKE MSEYCSTLCR HLYLFPGHPP T

Purification: SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Alternative Name: CASP2

Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.

Molecular Weight: 66.54 kDa

UniProt: P42575

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway