CK1 epsilon Protein (AA 1-416, full length) (His tag)
Quick Overview for CK1 epsilon Protein (AA 1-416, full length) (His tag) (ABIN5709343)
Target
See all CK1 epsilon (CSNK1E) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- full length, AA 1-416
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Purification tag / Conjugate
- This CK1 epsilon protein is labelled with His tag.
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Sequence
- MELRVGNKYR LGRKIGSGSF GDIYLGANIA SGEEVAIKLE CVKTKHPQLH IESKFYKMMQ GGVGIPSIKW CGAEGDYNVM VMELLGPSLE DLFNFCSRKF SLKTVLLLAD QMISRIEYIH SKNFIHRDVK PDNFLMGLGK KGNLVYIIDF GLAKKYRDAR THQHIPYREN KNLTGTARYA SINTHLGIEQ SRRDDLESLG YVLMYFNLGS LPWQGLKAAT KRQKYERISE KKMSTPIEVL CKGYPSEFST YLNFCRSLRF DDKPDYSYLR QLFRNLFHRQ GFSYDYVFDW NMLKFGAARN PEDVDRERRE HEREERMGQL RGSATRALPP GPPTGATANR LRSAAEPVAS TPASRIQPAG NTSPRAISRV DRERKVSMRL HRGAPANVSS SDLTGRQEVS RIPASQTSVP FDHLGK
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Purification
- SDS-PAGE
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Casein Kinase 1, epsilon (CSNK1E) (AA 1-416) protein (His tag)
custom-made CSNK1E Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Casein Kinase 1, epsilon (CSNK1E) (AA 1-416) protein (His tag)custom-made CSNK1E Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Casein Kinase 1, epsilon (CSNK1E) (AA 1-416) protein (GST tag)CSNK1E Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Casein Kinase 1, epsilon (CSNK1E) (AA 17-231) protein (GST tag)CSNK1E Origin: Human Host: Escherichia coli (E. coli) Recombinant 95 % ELISA
Casein Kinase 1, epsilon (CSNK1E) (AA 1-416), (full length) protein (His tag)CSNK1E Origin: Human Host: Yeast Recombinant > 90 % SDS
Casein Kinase 1, epsilon (CSNK1E) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CSNK1E Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Casein Kinase 1, epsilon (CSNK1E) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CSNK1E Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Storage
- -80 °C,4 °C,-20 °C
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Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))
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Alternative Name
- KC1E
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Background
- Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.
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Molecular Weight
- 51.4 kDa
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UniProt
- P49674
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Pathways
- Hedgehog Signaling, M Phase
Target
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