Density Regulated Protein Protein (AA 2-198) (His-SUMO Tag)
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- Target See all Density Regulated Protein (DENR) Proteins
- Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-198
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Density Regulated Protein protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- AADISESSGA DCKGDPRNSA KLDADYPLRV LYCGVCSLPT EYCEYMPDVA KCRQWLEKNF PNEFAKLTVE NSPKQEAGIS EGQGTAGEEE EKKKQKRGGR GQIKQKKKTV PQKVTIAKIP RAKKKYVTRV CGLATFEIDL KEAQRFFAQK FSCGASVTGE DEIIIQGDFT DDIIDVIQEK WPEVDDDSIE DLGEVKK
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product DENR Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))
- Alternative Name
- DENR (DENR Products)
- Background
- May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation, promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
- Molecular Weight
- 37.9 kDa
- UniProt
- O43583
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