EIF3G Protein (AA 2-320) (His-SUMO Tag)
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- Target See all EIF3G Proteins
- EIF3G (Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-320
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This EIF3G protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- PTGDFDSKPS WADQVEEEGE DDKCVTSELL KGIPLATGDT SPEPELLPGA PLPPPKEVIN GNIKTVTEYK IDEDGKKFKI VRTFRIETRK ASKAVARRKN WKKFGNSEFD PPGPNVATTT VSDDVSMTFI TSKEDLNCQE EEDPMNKLKG QKIVSCRICK GDHWTTRCPY KDTLGPMQKE LAEQLGLSTG EKEKLPGELE PVQATQNKTG KYVPPSLRDG ASRRGESMQP NRRADDNATI RVTNLSEDTR ETDLQELFRP FGSISRIYLA KDKTTGQSKG FAFISFHRRE DAARAIAGVS GFGYDHLILN VEWAKPSTN
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product EIF3G Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- EIF3G (Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G))
- Alternative Name
- EIF3G (EIF3G Products)
- Background
- Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassbly and recycling of post-termination ribosomal complexes and subsequently prevents prature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.
- Molecular Weight
- 51.46 kDa
- UniProt
- O75821
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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