tau Protein (AA 2-752) (His tag)
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- Target See all tau Proteins
- tau (tau Protein)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-752
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Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This tau protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- AEPRQEFDTM EDQAGDYTML QDQEGDMDHG LKESPPQPPA DDGSEEPGSE TSDAKSTPTA EDVTAPLVEE RAPDKQATAQ SHTEIPEGTT AEEAGIGDTP NMEDQAAGHV TQEPQKVEIF SQSLLVEPGR REGQAPDSGI SDWTHQQVPS MSGAPLPPQG LREATHQPLG TRPEDVERSH PASELLWQES PQKEAWGKDR LGSEEEVDED ITMDESSQES PPSQASLAPG TATPQARSVS ASGVSGETTS IPGFPAEGSI PLPADFFSKV SAETQASPPE GPGTGPSEEG HEAAPEFTFH VEIKASAPKE QDLEGATVVG APAEEQKARG PSVGKGTKEA SLLEPTDKQP AAGLPGRPVS RVPQLKARVA GVSKDRTGND EKKAKTSTPS CAKTPSNRPC LSPTRPTPGS SDPLIKPSSP AVCPEPATSP KYVSSVTPRN GSPGTKQMKL KGADGKTGAK IATPRGAATP GQKGTSNATR IPAKTTPSPK TPPGSGEPPK SGERSGYSSP GSPGTPGSRS RTPSLPTPPT REPKKVAVVR TPPKSPSASK SRLQTAPVPM PDLKNVRSKI GSTENLKHQP GGGKVQIINK KLDLSNVQSK CGSKDNIKHV PGGGSVHIVY KPVDLSKVTS KCGSLGNIHH KPGGGQVEVK SEKLDFKDRV QSKIGSLDNI THVPGGGNKK IETHKLTFRE NAKAKTDHGA EIVYKSPVVS GDTSPRHLSN VSSTGSIDMV DSPQLATLAD EVSASLAKQG L
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product tau Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- tau (tau Protein)
- Alternative Name
- tau (tau Products)
- Background
- Promotes microtubule assbly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma mbrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
- Molecular Weight
- 82.5 kDa
- UniProt
- P19332
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