Nephrin Protein (AA 23-257) (His tag)

Catalog No. ABIN5710021

This Recombinant Nephrin protein is expressed in Escherichia coli (E. coli).

Quick Overview for Nephrin Protein (AA 23-257) (His tag) (ABIN5710021)

Target: Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 %

Product Details

Protein Characteristics: AA 23-257

Purification tag / Conjugate: This Nephrin protein is labelled with His tag.

Sequence: QLAIPASVPR GFWALPENLT VVEGASVELR CGVSTPGSAV QWAKDGLLLG PDPRIPGFPR YRLEGDPARG EFHLHIEACD LSDDAEYECQ VGRSEMGPEL VSPRVILSIL VPPKLLLLTP EAGTMVTWVA GQEYVVNCVS GDAKPAPDIT ILLSGQTISD ISANVNEGSQ QKLFTVEATA RVTPRSSDNR QLLVCEASSP ALEAPIKASF TVNVLFPPGP PVIEWPGLDE GHVRA

Purification: SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))

Alternative Name: NPHN

Background: Ses to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion .

Molecular Weight: 29.16 kDa

UniProt: O60500

Pathways: Regulation of Actin Filament Polymerization, Skeletal Muscle Fiber Development