PPM1B Protein (AA 2-193) (His-SUMO Tag)
Quick Overview for PPM1B Protein (AA 2-193) (His-SUMO Tag) (ABIN5710135)
Target
See all PPM1B ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 2-193
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Purification tag / Conjugate
- This PPM1B protein is labelled with His-SUMO Tag.
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Sequence
- MSIVLVCFSN APKVSDEAVK KDSELDKHLE SRVEEIMEKS GEEGMPDLAH VMRILSAENI PNLPPGGGLA GKRNVIEAVY SRLNPHRESD GASDEAEESG SQGKLVEALR QMRINHRGNY RQLLEEMLTS YRLAKVEGEE SPAEPAATAT SSNSDAGNPV TMQESHTESE SGLAELDSSN EDAGTKMSGE KI
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Purification
- SDS-PAGE
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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B) (AA 1-192) protein (GST tag)
PPM1B Origin: Human Host: Wheat germ Recombinant ELISA, AP, AA, WB
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PPM1B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)PPM1B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PPM1B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Storage
- -80 °C,4 °C,-20 °C
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Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))
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Alternative Name
- PPM1B
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Background
- Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
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Molecular Weight
- 36.74 kDa
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UniProt
- O75688
Target
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