Melanoma gp100 Protein (AA 25-467) (His-SUMO Tag)
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- Target See all Melanoma gp100 (PMEL) Proteins
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-467
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Melanoma gp100 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- KVPRNQDWLG VSRQLRTKAW NRQLYPEWTE AQRLDCWRGG QVSLKVSNDG PTLIGANASF SIALNFPGSQ KVLPDGQVIW VNNTIINGSQ VWGGQPVYPQ ETDDACIFPD GGPCPSGSWS QKRSFVYVWK TWGQYWQVLG GPVSGLSIGT GRAMLGTHTM EVTVYHRRGS RSYVPLAHSS SAFTITDQVP FSVSVSQLRA LDGGNKHFLR NQPLTFALQL HDPSGYLAEA DLSYTWDFGD SSGTLISRAL VVTHTYLEPG PVTAQVVLQA AIPLTSCGSS PVPGTTDGHR PTAEAPNTTA GQVPTTEVVG TTPGQAPTAE PSGTTSVQVP TTEVISTAPV QMPTAESTGM TPEKVPVSEV MGTTLAEMST PEATGMTPAE VSIVVLSGTT AAQVTTTEWV ETTARELPIP EPEGPDASSI MSTESITGSL GPLLDGTATL RLV
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product PMEL Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Alternative Name
- PMEL (PMEL Products)
- Background
- Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
- Molecular Weight
- 63 kDa
- UniProt
- P40967
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