ICT1 Protein (AA 30-206) (His-SUMO Tag)

Catalog No. ABIN5711249

This Recombinant ICT1 protein is produced in Escherichia coli (E. coli).

Quick Overview for ICT1 Protein (AA 30-206) (His-SUMO Tag) (ABIN5711249)

Target: ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 %

Product Details

Protein Characteristics: AA 30-206

Purification tag / Conjugate: This ICT1 protein is labelled with His-SUMO Tag.

Sequence: LHKQKDGTEF KSIYSLDKLY PESQGSDTAW RVPNGAKQAD SDIPLDRLTI SYCRSSGPGG QNVNKVNSKA EVRFHLATAE WIAEPVRQKI AITHKNKINR LGELILTSES SRYQFRNLAD CLQKIRDMIT EASQTPKEPT KEDVKLHRIR IENMNRERLR QKRIHSAVKT SRRVDMD

Purification: SDS-PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))

Alternative Name: ICT1

Background: Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been praturely terminated and thus in the recycling of stalled mitochondrial ribosomes.

Molecular Weight: 36.4 kDa

UniProt: Q14197