WT1 Protein (AA 147-446, partial) (His tag)
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- Target See all WT1 Proteins
- WT1 (Wilms Tumor 1 (WT1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 147-446, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This WT1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MEKGYSTVTF DGTPSYGHTP SHHAAQFPNH SFKHEDPMGQ QGSLGEQQYS VPPPVYGCHT PTDSCTGSQA LLLRTPYSSD NLYQMTSQLE CMTWNQMNLG ATLKGVAAGS SSSVKWTEGQ SNHSTGYESD NHTTPILCGA QYRIHTHGVF RGIQDVRRVP GVAPTLVRSA SETSEKRPFM CAYPGCNKRY FKLSHLQMHS RKHTGEKPYQ CDFKDCERRF SRSDQLKRHQ RRHTGVKPFQ CKTCQRKFSR SDHLKTHTRT HTGEKPFSCR WPSCQKKFAR SDELVRHHNM HQRNMTKLQ
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product WT1 Protein
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Wilms Tumor 1 (WT1) (AA 1-449) protein (His tag)
custom-made WT1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Wilms Tumor 1 (WT1) (AA 157-445) protein (His tag)WT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Wilms Tumor 1 (WT1) (AA 349-439) protein (GST tag)WT1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Wilms Tumor 1 (WT1) (AA 1-302) protein (GST tag)WT1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Wilms Tumor 1 (WT1) (AA 1-449), (full length) protein (His-SUMO Tag)WT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- WT1 (Wilms Tumor 1 (WT1))
- Alternative Name
- WT1 (WT1 Products)
- Background
- Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital syst. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
- Molecular Weight
- 38.2 kDa
- UniProt
- P19544
- Pathways
- Tube Formation
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