CD163 Protein (CD163) (AA 86-365, partial) (His tag)
Quick Overview for CD163 Protein (CD163) (AA 86-365, partial) (His tag) (ABIN5714360)
Target
See all CD163 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- partial, AA 86-365
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Purification tag / Conjugate
- This CD163 protein is labelled with His tag.
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Sequence
- VVCQQLGCPT SIKALGWANS SAGSGYIWMD KVSCTGNESA LWDCKHDGWG KHNCTHEKDA GVTCSDGSNL EMRLVNSAGH RCLGRVEIKF QGKWGTVCDD NFSKDHASVI CKQLGCGSAI SFSGSAKLGA GSGPIWLDDL ACNGNESALW DCKHRGWGKH NCDHAEDVGV ICLEGADLSL RLVDGVSRCS GRLEVRFQGE WGTVCDDNWD LRDASVVCKQ LGCPTAISAI GRVNASEGSG QIWLDNISCE GHEATLWECK HQEWGKHYCH HREDAGVTCS
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Purification
- SDS-PAGE
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CD163 (CD163) (AA 39-1045) protein (His tag)
CD163 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD163 (CD163) (AA 42-1045) protein (His-Avi Tag)CD163 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD163 (CD163) (AA 42-1045) protein (His-Avi Tag,Biotin)CD163 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD163 (CD163) (AA 42-1050) protein (His tag)CD163 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
CD163 (CD163) (AA 44-1048) protein (His tag)CD163 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
CD163 (CD163) (AA 78-168) protein (GST tag)CD163 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Storage
- -80 °C,4 °C,-20 °C
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Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- CD163
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Alternative Name
- C163A
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Background
- Involved in clearance and endocytosis of hoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hoglobin/haptoglobin and subsequent breakdown of he. Binds hoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 .After shedding, the soluble form (sCD163) may play an anti-inflammatory role.
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Molecular Weight
- 32.2 kDa
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UniProt
- Q2VLH6
Target
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