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Osteoclast Associated Receptor (OSCAR) (AA 19-286) protein (His tag) Protein

OSCAR Origin: Human Source: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN5853004
$553.85
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100 μg ABIN5853004
100 μg ABIN5853004
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  • Protein Name
    Protein Type
    Recombinant
    Protein Characteristics
    AA 19-286
    Origin
    Human
    Source
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This OSCAR protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGSDITPSVA IIVPPASYHP KPWLGAQPAT VVTPGVNVTL RCRAPQPAWR FGLFKPGEIA PLLFRDVSSE LAEFFLEEVT PAQGGIYRCC YRRPDWGPGV WSQPSDVLEL LVTEELPRPS LVALPGPVVG PGANVSLRCA GRLRNMSFVL YREGVAAPLQ YRHSAQPWAD FTLLGARAPG TYSCYYHTPS APYVLSQRSE VLVISWEGEG PEARPASSAP GMQAPGPPPS DPGAQAPSLS SFRPRGLVLQ PLLPQTQDSW DPAPPPSDPG V
    Purity
    > 85 % by SDS - PAGE
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Denatured

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Protein Name
    Synonyms
    OSCAR, mOSCAR-M3, mOSCAR, mOSCAR-M1, mOSCAR-M2, PIGR3, PIgR-3, RGD1559897, osteoclast associated, immunoglobulin-like receptor, osteoclast-associated immunoglobulin-like receptor, osteoclast associated receptor, OSCAR, LOC748876, Oscar
    Background
    Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. OSCAR is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human OSCAR protein, fused to His-tag at N-terminus, was expressed in E.coli.
    Molecular Weight
    31kDa (291aa)
    NCBI Accession
    NP_996554
    UniProt
    Q8IYS5
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