OSCAR Products
(Osteoclast Associated Receptor (OSCAR))
Categories
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured OSCAR Categories
OSCAR Antibodies
High quality antibodies with extensive validation data.
OSCAR ELISA Kits
Reliable ELISA kits for a wide range of species.
OSCAR Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended OSCAR Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7140032
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (1)
Cat. No.
ABIN7426541
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN1536842
Quantity
400 μL
Datasheet
Datasheet
Recommended OSCAR ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6958339
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6975614
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN511453
Quantity
96 tests
Datasheet
Datasheet
Recommended OSCAR Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275377
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275378
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313704
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our OSCAR products
: "Parthenolide reduces empty lacunae and osteoclastic bone surface resorption induced by polyethylene particles in a murine calvarial model of peri-implant osteolysis." in: Journal of biomedical materials research. Part A, (2015) (PubMed).: "Caffeic acid phenethyl ester abrogates bone resorption in a murine calvarial model of polyethylene particle-induced osteolysis." in: Calcified tissue international, Vol. 96, Issue 6, pp. 565-74, (2015) (PubMed).
: "Placental growth factor and placental protein 13 in patients with Balkan endemic nephropathy, a worldwide disease." in: Renal failure, pp. 1-4, (2015) (PubMed).
: "Immune complexes regulate bone metabolism through FcRγ signalling." in: Nature communications, Vol. 6, pp. 6637, (2015) (PubMed).
: "The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints." in: Arthritis research & therapy, Vol. 14, Issue 6, pp. R245, (2014) (PubMed).
: "Quantitative proteomics reveals novel functions of osteoclast-associated receptor in STAT signaling and cell adhesion in human endothelial cells." in: Journal of molecular and cellular cardiology, Vol. 53, Issue 6, pp. 829-37, (2012) (PubMed).
: "Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis." in: The Journal of biological chemistry, Vol. 280, Issue 42, pp. 35209-16, (2005) (PubMed).
Synonyms and alternative names related to OSCAR
osteoclast associated, immunoglobulin-like receptor (OSCAR), osteoclast-associated immunoglobulin-like receptor (LOC748876), osteoclast associated receptor (Oscar), osteoclast associated, immunoglobulin-like receptor (Oscar), mOSCAR, mOSCAR-M1, mOSCAR-M2, mOSCAR-M3, OSCAR, PIgR-3, PIGR3, RGD1559897Protein level used designations for OSCAR
- osteoclast associated, immunoglobulin-like receptor
- osteoclast associated, immunoglobulin-like receptor, isoform 4
- ocl178
- osteoclast-associated immunoglobulin-like receptor
- osteoclast-associated receptor OSCAR
- osteoclast associated receptor OSCAR-S1
- osteoclast associated receptor OSCAR-S2
- poly-Ig receptor 3
- polymeric immunoglobulin receptor 3
- osteoclast associated receptor
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