PNRC2 Protein (AA 1-139) (His tag)
Quick Overview for PNRC2 Protein (AA 1-139) (His tag) (ABIN5853060)
Target
See all PNRC2 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-139
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Purification tag / Conjugate
- This PNRC2 protein is labelled with His tag.
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Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMGGGERY NIPAPQSRNV SKNQQQLNRQ KTKEQNSQMK IVHKKKERGH GYNSSAAAWQ AMQNGGKNKN FPNNQSWNSS LSGPRLLFKS QANQNYAGAK FSEPPSPSVL PKPPSHWVPV SFNPSDKEIM TFQLKTLLKV QV
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Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (AA 1-139) protein (His tag)
custom-made PNRC2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (AA 1-140) protein (His tag)custom-made PNRC2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Denatured
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))
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Alternative Name
- PNRC2
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Background
- PNRC2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. This protein may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. It is required for uPF1/RENT1 localization to the P-body and also acts as a nuclear receptor coactivator. PNRC2 may play a role in controlling the energy balance between energy storage and energy expenditure. Recombinant human PNCR2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
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Molecular Weight
- 18.0kDa (162aa)
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NCBI Accession
- NP_060231
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UniProt
- Q9NPJ4
Target
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