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GIMAP5 Protein (AA 1-284) (His tag)

GIMAP5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85% by SDS-PAGE SDS
Catalog No. ABIN5853229
  • Target See all GIMAP5 Proteins
    GIMAP5 (GTPase, IMAP Family Member 5 (GIMAP5))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-284
    Origin
    • 5
    • 2
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GIMAP5 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGSMGGFQRG KYGTMAEGRS EDNLSATPPA LRIILVGKTG CGKSATGNSI LGQPVFESKL RAQSVTRTCQ VKTGTWNGRK VLVVDTPSIF ESQADTQELY KNIGDCYLLS APGPHVLLLV IQLGRFTAQD TVAIRKVKEV FGTGAMRHVV ILFTHKEDLG GQALDDYVAN TDNCSLKDLV RECERRYCAF NNWGSVEEQR QQQAELLAVI ERLGREREGS FHSNDLFLDA QLLQRTGAGA CQEDYRQYQA KVEWQVEKHK QELRENESNW AYKALLRVKH LMLLHYE
    Purity
    > 85% by SDS-PAGE
    Top Product
    Discover our top product GIMAP5 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.2M NaCl, 40 % glycerol, 2  mM DTT
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Target
    GIMAP5 (GTPase, IMAP Family Member 5 (GIMAP5))
    Alternative Name
    GIMAP5 (GIMAP5 Products)
    Background
    GIMAP5 is a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36. 1. GIMAP5 is an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene. Recombinant human GIMAP5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
    Molecular Weight
    34.4 kDa (307aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_060854
    UniProt
    Q96F15
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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