PF4V1 Protein (AA 31-104) (His tag)

Catalog No. ABIN5853671

This Recombinant PF4V1 protein is expressed in Escherichia coli (E. coli).

Quick Overview for PF4V1 Protein (AA 31-104) (His tag) (ABIN5853671)

Target: PF4V1 (Platelet Factor 4 Variant 1 (PF4V1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 85% by SDS-PAGE

Product Details

Protein Characteristics: AA 31-104

Purification tag / Conjugate: This PF4V1 protein is labelled with His tag.

Sequence: FARAEAE EDGDLQCLCV KTTSQVRPRH ITSLEVIKAG PHCPTAQLIA TLKNGRKICL DLQALLYKKI IKEHLES

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.2M NaCl, 50 % glycerol, 1  mM DTT.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details

Target: PF4V1 (Platelet Factor 4 Variant 1 (PF4V1))

Alternative Name: PF4V1/CXCL4L1

Background: PF4V1 belongs to the intercrine alpha (chemokine CxC) family. It is a inhibitor of angiogenesis and inhibitor of endothelial cell chemotaxis (in vitro). Binding to heparin is much weaker than in the close homolog PF4/CXCL4. Recombinant human PF4V1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Molecular Weight: 10.6 kDa (97aa) confirmed by MALDI-TOF

NCBI Accession: NP_002611

UniProt: P10720