FHL2 Protein (AA 1-279) (His tag)
Quick Overview for FHL2 Protein (AA 1-279) (His tag) (ABIN5853936)
Target
See all FHL2 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 1-279
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Purification tag / Conjugate
- This FHL2 protein is labelled with His tag.
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Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMTERFDC HHCNESLFGK KYILREESPY CVVCFETLFA NTCEECGKPI GCDCKDLSYK DRHWHEACFH CSQCRNSLVD KPFAAKEDQL LCTDCYSNEY SSKCQECKKT IMPGTRKMEY KGSSWHETCF ICHRCQQPIG TKSFIPKDNQ NFCVPCYEKQ HAMQCVQCKK PITTGGVTYR EQPWHKECFV CTACRKQLSG QRFTARDDFA YCLNCFCDLY AKKCAGCTNP ISGLGGTKYI SFEERQWHND CFNCKKCSLS LVGRGFLTER DDILCPDCGK DI
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Denatured
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- FHL2 (Four and A Half LIM Domains 2 (FHL2))
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Alternative Name
- FHL2
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Background
- FHL2 is a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified. Recombinant human FHL2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
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Molecular Weight
- 34.6kDa (302aa)
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NCBI Accession
- NP_001034581
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UniProt
- Q14192
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
Target
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