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Cathepsin B Protein (CTSB) (AA 18-339) (His tag)

CTSB Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN5854523
  • Target See all Cathepsin B (CTSB) Proteins
    Cathepsin B (CTSB)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 18-339
    Origin
    • 16
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Source
    • 9
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This Cathepsin B protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    HDKPSFHPLS DDLINYINKQ NTTWQAGRNF YNVDISYLKK LCGTVLGGPK LPGRVAFGED IDLPETFDAR EQWSNCPTIG QIRDQGSCGS CWAFGAVEAI SDRTCIHTNG RVNVEVSAED LLTCCGIQCG DGCNGGYPSG AWSFWTKKGL VSGGVYNSHV GCLPYTIPPC EHHVNGSRPP CTGEGDTPRC NKSCEAGYSP SYKEDKHFGY TSYSVSNSVK EIMAEIYKNG PVEGAFTVFS DFLTYKSGVY KHEAGDMMGG HAIRILGWGV ENGVPYWLAA NSWNLDWGDN GFFKILRGEN HCGIESEIVA GIPRTDQYWG RFLEHHHHHH
    Purity
    > 90 % by SDS - PAGE
    Endotoxin Level
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
    Top Product
    Discover our top product CTSB Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    Cathepsin B (CTSB)
    Alternative Name
    Ctsb (CTSB Products)
    Background
    CTSB, also known as cathepsin B preproprotein, is a papain-family cysteine protease that is normally located in lysosomes. It has the ability to degrade several extracellular matrix components at both neutral and acidic  pH and has been implicated in the progression of several human and rodent tumors progression and arthritis. Recombinant mouse CTSB, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molecular Weight
    36.4kDa (330aa) 28-40kDa (SDS-PAGE under reducing conditions)
    NCBI Accession
    NP_031824
    UniProt
    P10605
    Pathways
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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