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Cathepsin B Protein (CTSB) (His tag)

CTSB Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7320464
  • Target See all Cathepsin B (CTSB) Proteins
    Cathepsin B (CTSB)
    Protein Type
    Recombinant
    Origin
    • 19
    • 10
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Source
    • 11
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This Cathepsin B protein is labelled with His tag.
    Purpose
    Recombinant Mouse Cathepsin B/CTSB Protein (His Tag)
    Sequence
    His18-Phe339
    Characteristics
    Recombinant Mouse Cathepsin B is produced by our Mammalian expression system and the target gene encoding His18-Phe339 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CTSB Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Cathepsin B (CTSB)
    Alternative Name
    Cathepsin B/CTSB (CTSB Products)
    Synonyms
    APPS Protein, CPSB Protein, CB Protein, apps Protein, cpsb Protein, LOC692390 Protein, CTSB Protein, cathepsin B Protein, cathepsin B S homeolog Protein, CTSB Protein, Ctsb Protein, ctsb.S Protein, LOC692390 Protein
    Background

    Background: Cathepsin B (CatB) is an enzymatic protein belonging to the peptidase (or protease) families. It is the first described member of the family of lysosomal cysteine proteases. It is known to process a number of proteins, including pro and active caspases, prorenin and secretory leucoprotease inhibitor (SLPI). It is believed to participate in intracellular degradation and turnover of proteins. Cathepsin B may play a role in activation and inactivation of caspases, activation of renin and inactivation of SLPI, the key steps in apoptosis, angiotensin production, and progression of emphysema, respectively. Cathepsin B may also have a role in invasion and metastasis.

    Synonym: Cathepsin B,Ctsb,Cathepsin B1

    Molecular Weight
    36.4 kDa
    UniProt
    P10605
    Pathways
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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