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14-3-3 eta Protein (YWHAH) (AA 1-246)

This Recombinant 14-3-3 eta protein is expressed in Escherichia coli (E. coli).
Catalog No. ABIN5854575

Quick Overview for 14-3-3 eta Protein (YWHAH) (AA 1-246) (ABIN5854575)

Target

See all 14-3-3 eta (YWHAH) Proteins
14-3-3 eta (YWHAH)

Protein Type

Recombinant

Origin

  • 7
  • 1
  • 1
Human

Source

  • 5
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 90 % by SDS - PAGE
  • Protein Characteristics

    AA 1-246

    Sequence

    MGDREQLLQR ARLAEQAERY DDMASAMKAV TELNEPLSNE DRNLLSVAYK NVVGARRSSW RVISSIEQKT MADGNEKKLE KVKAYREKIE KELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP IRLGLALNFS VFYYEIQNAP EQACLLAKQA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDE EAGEGN
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target

    14-3-3 eta (YWHAH)

    Alternative Name

    14-3-3 eta

    Background

    14-3-3 eta also as known as YWHAH. This protein belong to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 eta interacts with and relocalizes the A20 zinc finger protein from the insoluble to the soluble fraction, suggesting a chaperone function. It implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binding to a large number of partners, usually by recognition of a phosphothreonine motif. Recombinant Human 14-3-3 eta was expressed in E.coli and purified by using conventional chromatography techniques.

    Molecular Weight

    28.2kDa (246aa)

    NCBI Accession

    NP_003396

    UniProt

    Q04917

    Pathways

    Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction
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