IL18BP Protein (AA 31-194) (hIgG-His-tag)
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- Target See all IL18BP Proteins
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 31-194
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This IL18BP protein is labelled with hIgG-His-tag.
- Application
- SDS-PAGE (SDS)
- Sequence
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TPVSQTT TAATASVRST KDPCPSQPPV FPAAKQCPAL EVTWPEVEVP LNGTLSLSCV ACSRFPNFSI LYWLGNGSFI EHLPGRLWEG STSRERGSTG TQLCKALVLE QLTPALHSTN FSCVLVDPEQ VVQRHVVLAQ LWAGLRATLP PTQEALPSSH SSPQQQG - Purity
- > 90% by SDS-PAGE
- Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product IL18BP Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- Alternative Name
- IL-18BP (IL18BP Products)
- Background
- IL18BP, as known as interleukin-18-binding protein isoform, is a secreted glycoprotein. It belongs to the interleukin 1 receptor family. This protein functions as an IL18 antagonist by binding to IL18 and blocking its biological activity. Also, it is essential for IL18 meditated signal transduction. The expression of IL18BP is markedly upregulated by IFN-gamma, suggesting that IL18 activity is modulated by a negative feedback mechanism meditated by IL18BP. Recombinant human IL18BP, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 44.9 kDa (406aa)
- NCBI Accession
- NP_001138529
- UniProt
- O95998
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