Ephrin B3 Protein (EFNB3) (AA 28-226) (His tag)
-
- Target See all Ephrin B3 (EFNB3) Proteins
- Ephrin B3 (EFNB3)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-226
-
Origin
- Human
-
Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This Ephrin B3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPLSLEPVY WNSANKRFQA EGGYVLYPQI GDRLDLLCPR ARPPGPHSSP NYEFYKLYLV GGAQGRRCEA PPAPNLLLTC DRPDLDLRFT IKFQEYSPNL WGHEFRSHHD YYIIATSDGT REGLESLQGG VCLTRGMKVL LRVGQSPRGG AVPRKPVSEM PMERDRGAAH SLEPGKENLP GDPTSNATSR GAEGPLPPPS MPHHHHHH
- Purity
- > 95 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
-
Ephrin B3 (EFNB3) protein (His tag)
EFNB3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Ephrin B3 (EFNB3) (AA 28-227) protein (His tag)EFNB3 Origin: Mouse Host: Yeast Recombinant > 90 % SDS
Ephrin B3 (EFNB3) (AA 28-227) protein (His tag)EFNB3 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- Target
- Ephrin B3 (EFNB3)
- Alternative Name
- EFNB3 (EFNB3 Products)
- Background
- EFNB3, also known as ephrin-B3, is a member of the Ephrin-B family of transmembrane ligands that bind and induce the tyrosine autophosphorylation of Eph receptors. EFNB3 is expressed on oligodendrocytes and neurons in the hippocampus and along the midline of the spinal cord. It is up-regulated in glioma and promotes tumor cell invasion and migration. This protein acts as the midline barrier that prevents corticospinal tract projections from recrossing when they enter the spinal gray matter. Recombinant human EFNB3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 23.0kDa (208aa) 28-40KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_001397
- UniProt
- Q15768
- Pathways
- RTK Signaling
-
