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FGFR2 alpha (AA 22-378) protein (hIgG-His-tag)

Recombinant protein expressed in Baculovirus infected Insect Cells.
Catalog No. ABIN5854934

Quick Overview for FGFR2 alpha (AA 22-378) protein (hIgG-His-tag) (ABIN5854934)

Target

FGFR2 alpha

Protein Type

Recombinant

Origin

  • 3
  • 1
Human

Source

  • 4
Baculovirus infected Insect Cells

Application

SDS-PAGE (SDS)

Purity

> 95% by SDS-PAGE
  • Protein Characteristics

    AA 22-378

    Purification tag / Conjugate

    hIgG-His-tag

    Sequence

    RPSFSLVEDT TLEPEEPPTK YQISQPEVYV AAPGESLEVR CLLKDAAVIS WTKDGVHLGP NNRTVLIGEY LQIKGATPRD SGLYACTASR TVDSETWYFM VNVTDAISSG DDEDDTDGAE DFVSENSNNK RAPYWTNTEK MEKRLHAVPA ANTVKFRCPA GGNPMPTMRW LKNGKEFKQE HRIGGYKVRN QHWSLIMESV VPSDKGNYTC VVENEYGSIN HTYHLDVVER SPHRPILQAG LPANASTVVG GDVEFVCKVY SDAQPHIQWI KHVEKNGSKY GPDGLPYLKV LKHSGINSSN AEVLALFNVT EADAGEYICK VSNYIGQANQ SAWLTVLPKQ QAPGREKEIT ASPDYLE

    Endotoxin Level

    < 1 EU per 1ug of protein (determined by LAL method)
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Target

    FGFR2 alpha

    Alternative Name

    FGF R2 alpha

    Background

    FGFR2, also known as fibroblast growth factor receptor 2 isoform 2, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. It plays an important regulatory role in skeletal development and bone formation. Its dysregulation results in a spectrum of bone and skin pathologies and several types of cancer. Recombinant human FGFR2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

    Molecular Weight

    66.6 kDa (596aa)

    NCBI Accession

    NP_075259

    UniProt

    P21802
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