FGFR2 Protein (AA 22-378) (hIgG-His-tag)
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- Target See all FGFR2 Proteins
- FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-378
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This FGFR2 protein is labelled with hIgG-His-tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- RPSFSLVEDT TLEPEEPPTK YQISQPEVYV AAPGESLEVR CLLKDAAVIS WTKDGVHLGP NNRTVLIGEY LQIKGATPRD SGLYACTASR TVDSETWYFM VNVTDAISSG DDEDDTDGAE DFVSENSNNK RAPYWTNTEK MEKRLHAVPA ANTVKFRCPA GGNPMPTMRW LKNGKEFKQE HRIGGYKVRN QHWSLIMESV VPSDKGNYTC VVENEYGSIN HTYHLDVVER SPHRPILQAG LPANASTVVG GDVEFVCKVY SDAQPHIQWI KHVEKNGSKY GPDGLPYLKV LKHSGINSSN AEVLALFNVT EADAGEYICK VSNYIGQANQ SAWLTVLPKQ QAPGREKEIT ASPDYLELEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSRDE LTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK HHHHHH
- Purity
- > 95 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product FGFR2 Protein
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Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 22-374) protein (His tag)
FGFR2 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 1-723) protein (GST tag)FGFR2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 400-821) (Active) protein (GST tag,His tag)FGFR2 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 92 % as determined by reducing SDS-PAGE. Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
- Alternative Name
- FGFR2 (FGFR2 Products)
- Background
- FGFR2, also known as fibroblast growth factor receptor 2 isoform 2, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. It plays an important regulatory role in skeletal development and bone formation. Its dysregulation results in a spectrum of bone and skin pathologies and several types of cancer. Recombinant human FGFR2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 66.6kDa (596aa) 70-100kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_075259
- UniProt
- P21802
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
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