CD81 Protein (CD81) (AA 113-201) (hIgG-His-tag)
Quick Overview for CD81 Protein (CD81) (AA 113-201) (hIgG-His-tag) (ABIN5854988)
Target
See all CD81 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 113-201
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Purification tag / Conjugate
- This CD81 protein is labelled with hIgG-His-tag.
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Sequence
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FVNKDQI AKDVKQFYDQ ALQQAVVDDD ANNAKAVVKT FHETLDCCGS STLTALTTSV LKNNLCPSGS NIISNLFKED CHQKIDDLFS GK -
Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- CD81
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Alternative Name
- CD81
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Background
- CD81, also known as CD81 antigen isoform 1, belongs to the tetraspanin family. It interacts directly with immunoglobulin superfamily member 8 (IGSF8, CD316) and CD36. In B cells, it is part of a complex with CD21, CD19 and Leu13. This complex reduces the threshold for B cell activation through B cell receptors by linking Ag specific recognition and CD21 mediator recognition. On T cells it associates with CD4 and CD8 and provides a costimulatory signal with CD3. Recombinant human CD81, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Molecular Weight
- 37 kDa (331aa)
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NCBI Accession
- NP_004347
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UniProt
- P60033
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Pathways
- Inositol Metabolic Process, Hepatitis C
Target
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