LAMP1 Protein (AA 29-382) (His tag)

Catalog No. ABIN5855031

This Recombinant LAMP1 protein is produced in Baculovirus infected Insect Cells.

Quick Overview for LAMP1 Protein (AA 29-382) (His tag) (ABIN5855031)

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Application: SDS-PAGE (SDS)

Purity: > 90% by SDS-PAGE

Product Details

Protein Characteristics: AA 29-382

Purification tag / Conjugate: This LAMP1 protein is labelled with His tag.

Sequence: ADPAMFMVKN GNGTACIMAN FSAAFSVNYD TKSGPKNMTF DLPSDATVVL NRSSCGKENT SDPSLVIAFG RGHTLTLNFT RNATRYSVQL MSFVYNLSDT HLFPNASSKE IKTVESITDI RADIDKKYRC VSGTQVHMNN VTVTLHDATI QAYLSNSSFS RGETRCEQDR PSPTTAPPAP PSPSPSPVPK SPSVDKYNVS GTNGTCLLAS MGLQLNLTYE RKDNTTVTRL LNINPNKTSA SGSCGAHLVT LELHSEGTTV LLFQFGMNAS SSRFFLQGIQ LNTILPDARD PAFKAANGSL RALQATVGNS YKCNAEEHVR VTKAFSVNIF KVWVQAFKVE GGQFGSVEEC LLDENSMHHH HHH

Endotoxin Level: < 1 EU per 1ug of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Alternative Name: CD107a/LAMP1

Background: LAMP1, also known as lysosome-associated membrane glycoprotein 1, is a membrane protein that belongs to the LAMP family. It is expressed in the endosome-lysosome membranes of cells, but is also found on the plasma membrane during the activation of NK cells, CD8+ T cells, mast cells, basophils, monocytes, and platelets. A glycoform of LAMP1 is expressed on the surface of activated macrophages where it promotes T cell co-stimulation and a Th1 biased immune response. Recombinant human LAMP1 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 39.4 kDa (363aa)

NCBI Accession: NP_005552

UniProt: P11279

Pathways: Autophagy