LDL Protein

Catalog No. ABIN622852

This LDL protein is produced in Human.

Quick Overview for LDL Protein (ABIN622852)

Target: LDL (Low Density Lipoprotein (LDL))

Origin: Human

Source: Human

Purity: Cholesterol level > 200mg/l. > = 1 % HDL.

Product Details

Characteristics: Low Density Lipoprotein

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

Target Details

Target: LDL (Low Density Lipoprotein (LDL))

Alternative Name: Low Density Lipoprotein

Background: LDL is a low-density lipoprotein that transports cholesterol and triglycerides from the liver to peripheral tissues. LDL (like all lipoproteins) facilitates the movement of fats and cholesterol within the water based solution of the blood stream. Each natural LDL particle contains a single Apo B-100 molecule (apolipoprotein B-100 is a protein with 4536 amino acid residues) that circulates the fatty acids and keeps them soluble in the aqueous environment. Additionally, the LDL core is highly-hydrophobic, consisting of linoleate (a polyunsaturated fatty acid) and about 1500 esterified cholesterol molecules. This core is enclosed by a shell of phospholipids and unesterified cholesterol in addition to a single copy of B-100 large protein (514 kD). Even though the LDL particles are approximately 22 nm in diameter and have a mass of about 3 million Daltons, they have a mass and size distribution since the LDL particles contain a varying number of fatty acids. LDL receptors are synthesized and placed in the plasma membrane when a cell requires cholesterol.