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CD38 Protein (AA 44-301) (His tag)

Recombinant CD38 protein expressed in HEK-293 Cells.
Catalog No. ABIN6253545
$495.08
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Quick Overview for CD38 Protein (AA 44-301) (His tag) (ABIN6253545)

Target

See all CD38 Proteins
CD38

Protein Type

Recombinant

Origin

  • 23
  • 11
  • 6
  • 4
  • 1
Cynomolgus

Source

  • 15
  • 10
  • 7
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

>95 % as determined by SDS-PAGE.
  • Protein Characteristics

    AA 44-301

    Purification tag / Conjugate

    This CD38 protein is labelled with His tag.

    Sequence

    AA 44-301

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    50 mM MES, 100 mM NaCl, pH 6.5

    Handling Advice

    Please avoid repeated freeze-thaw cycles.

    Storage

    -20 °C
  • Target

    CD38

    Background

    CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.

    Molecular Weight

    31.8 kDa

    NCBI Accession

    NP_001274206
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