MAP2K3 Protein (AA 1-318) (His tag)

Catalog No. ABIN6386730

Product Details

Target: MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))

Protein Type: Recombinant

Protein Characteristics: AA 1-318

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This MAP2K3 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: MAP2K3, 1-318aa, Human, His tag, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol

Storage: 4 °C

Target Details

Target: MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))

Alternative Name: MAP2K3 (MAP2K3 Products)

Background: MAP2K3, also known as dual specificity mitogen-activated protein kinase kinase 3, is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Recombinant human MAP2K3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Dual specificity mitogen-activated protein kinase kinase 3, MAPKK3, MEK3, MKK3, PRKMK3. NCBI no.: NP_002747

Molecular Weight: 38.3 kDa (338aa), confirmed by MALDI-TOF

Pathways: MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2