ARHGDIB Protein (AA 1-201) (GST tag)
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- Target See all ARHGDIB Proteins
- ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-201
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ARHGDIB protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
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MTE KAPEPHVEED DDDELDSKLN YKPPPQKSLK ELQEMDKDDE SLIKYKKTLL GDGPVVTDPK APNVVVTRLT LVCESAPGPI TMDLTGDLEA LKKETIVLKE GSEYRVKIHF KVNRDIVSGL KYVQHTYRTG VKVDKATFMV GSYGPRPEEY EFLTPVEEAP KGMLARGTYH NKSFFTDDDK QDHLSWEWNL SIKKEWTE - Purification
- purified by chromatography
- Purity
- > 90% by SDS-PAGE
- Top Product
- Discover our top product ARHGDIB Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- phosphate-buffered Saline(pH 7.4) containing 10% glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))
- Alternative Name
- ARHGDIB (ARHGDIB Products)
- Background
- Members of the Rho (or ARH) protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases. Recombinant human ARHGDIB protein, fused to GST-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 49.4 kDa (428aa)
- NCBI Accession
- NP_001166
- Pathways
- Caspase Cascade in Apoptosis
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