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PGC Protein (AA 17-388) (His tag)

PGC Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS
Catalog No. ABIN6387837
  • Target See all PGC Proteins
    PGC (Pepsinogen C (PGC))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 17-388
    Origin
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 10
    • 5
    • 3
    • 2
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This PGC protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    AVVKVPLKKF KSIRETMKEK GLLGEFLRTH KYDPAWKYRF GDLSVTYEPM AYMDAAYFGE ISIGTPPQNF LVLFDTGSSN LWVPSVYCQS QACTSHSRFN PSESSTYSTN GQTFSLQYGS GSLTGFFGYD TLTVQSIQVP NQEFGLSENE PGTNFVYAQF DGIMGLAYPA LSVDEATTAM QGMVQEGALT SPVFSVYLSN QQGSSGGAVV FGGVDSSLYT GQIYWAPVTQ ELYWQIGIEE FLIGGQASGW CSEGCQAIVD TGTSLLTVPQ QYMSALLQAT GAQEDEYGQF LVNCNSIQNL PSLTFIINGV EFPLPPSSYI LSNNGYCTVG VEPTYLSSQN GQPLWILGDV FLRSYYSVYD LGNNRVGFAT AA
    Purity
    > 95% by SDS-PAGE
    Endotoxin Level
    < 1 EU per 1ug of protein (determined by LAL method)
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Target
    PGC (Pepsinogen C (PGC))
    Alternative Name
    Pepsinogen C/PGC (PGC Products)
    Background
    PGC, also known as gastricsin, is an aspartic proteinase that belongs to the peptidase family A1. It is synthesized in the gastric mucosa as inactive precursors. It contains a prosegment that serves to stabilize the inactive form and prevent entry of the substrate to the active site. Serum levels of PGC are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Recombinant human PGC, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques
    Molecular Weight
    41.6 kDa (380aa)
    NCBI Accession
    NP_002621
    UniProt
    P20142
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