Relaxin 2 Protein (RLN2) (AA 25-185) (His tag)

Catalog No. ABIN6387989

Recombinant Relaxin 2 protein expressed in Baculovirus infected Insect Cells.

Quick Overview for Relaxin 2 Protein (RLN2) (AA 25-185) (His tag) (ABIN6387989)

Target: Relaxin 2 (RLN2)

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Application: SDS-PAGE (SDS)

Purity: > 85% by SDS-PAGE

Product Details

Protein Characteristics: AA 25-185

Purification tag / Conjugate: This Relaxin 2 protein is labelled with His tag.

Sequence: ADPDSWMEEV IKLCGRELVR AQIAICGMST WSKRSLSQED APQTPRPVAE IVPSFINKDT ETINMMSEFV ANLPQELKLT LSEMQPALPQ LQQHVPVLKD SSLLFEEFKK LIRNRQSEAA DSSPSELKYL GLDTHSRKKR QLYSALANKC CHVGCTKRSL ARFCHHHHHH

Endotoxin Level: < 1 EU per 1ug of protein (determined by LAL method)

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details

Target: Relaxin 2 (RLN2)

Alternative Name: Relaxin-2

Background: RLN2, as known as prorelaxin H2 isoform 1, belongs to the insulin gene superfamily. This family is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. It is 18 kDa in size and 185 aa in length. It contains a 24 aa signal sequence, a 3. 3 kDa, 29 aa B domain, a 106 aa C (or connecting) domain, and a C-terminal, 2. 7 kDa, 24 aa A domain. Recombinant human RLN2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molecular Weight: 19.3 kDa (170aa)

NCBI Accession: NP_604390

UniProt: P04090

Pathways: Hormone Activity