CD20 Protein (AA 210-297) (His tag)
Quick Overview for CD20 Protein (AA 210-297) (His tag) (ABIN6388166)
Target
See all CD20 (MS4A1) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 210-297
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Purification tag / Conjugate
- This CD20 protein is labelled with His tag.
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Sequence
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GIVENEW KRTCSRPKSN IVLLSAEEKK EQTIEIKEEV VGLTETSSQP KNEEDIEIIP IQEEEEEETE TNFPEPPQDQ ESSPIENDSS P -
Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
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Alternative Name
- MS4A1/CD20
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Background
- MS4A1, also known as B-lymphocyte antigen CD20, is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase and progressively increasing in concentration until maturity. It is to enable optimal B-cell immune response, specifically against T-independent antigens. It is suspected that it acts as a calcium channel in the cell membrane. It plays a role in the microenvironmental interactions of B cells. This structurally unique phosphoprotein plays a role in the regulation of human B cell proliferation and differentiation. It was strongly phosphorylated on resting B cells after CDw40 stimulation, suggesting that it may be functionally regulated by a protein kinase. Recombinant human MS4A1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Molecular Weight
- 11.1 kDa (97aa)
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NCBI Accession
- NP_068769
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UniProt
- P11836
Target
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