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CD52 Protein (CD52) (AA 25-36) (hIgG-His-tag)

CD52 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS
Catalog No. ABIN6388178
  • Target See all CD52 Proteins
    CD52
    Protein Type
    Recombinant
    Protein Characteristics
    AA 25-36
    Origin
    • 11
    • 1
    Human
    Source
    • 8
    • 2
    • 1
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This CD52 protein is labelled with hIgG-His-tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    GQNDTSQTSS PSLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H
    Purity
    > 95% by SDS-PAGE
    Endotoxin Level
    < 1 EU per 1ug of protein (determined by LAL method)
    Top Product
    Discover our top product CD52 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Target
    CD52
    Alternative Name
    CD52 (CD52 Products)
    Background
    CD52, also known as CAMPATH-1 antigen, is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein that is tethered to the cell surface with a GPI linkage. This protein can be targeted to induce immune suppression by complement-meditated cell lysis. CD52 is expressed on lymphocytes, monocytes, monocytes-derived dendritic cells, eosinophils, and neutrophils, but not on the stem cells from which these lymphocytes were derived. Also, it is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. Recombinant human CD52, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molecular Weight
    28.2 kDa (251aa)
    NCBI Accession
    NP_001794
    UniProt
    P31358
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