CD52 Protein (CD52) (AA 25-36) (hIgG-His-tag)
Quick Overview for CD52 Protein (CD52) (AA 25-36) (hIgG-His-tag) (ABIN6388178)
Target
See all CD52 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 25-36
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Purification tag / Conjugate
- This CD52 protein is labelled with hIgG-His-tag.
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Sequence
- GQNDTSQTSS PSLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H
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Endotoxin Level
- < 1 EU per 1ug of protein (determined by LAL method)
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CD52 (CD52) (AA 25-36) protein (mFc Tag)
CD52 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD52 (CD52) (AA 24-47) protein (Fc Tag)CD52 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD52 (CD52) (AA 25-36) protein (Fc Tag)CD52 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD52 (CD52) protein (Biotin)CD52 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
CD52 (CD52) (AA 25-36) (Active) protein (Fc Tag)CD52 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD52 (CD52) (AA 25-36) (Active) protein (His tag,AVI tag,Biotin)CD52 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD52 (CD52) (AA 25-36) (Active) protein (Fc Tag,AVI tag,Biotin)CD52 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- CD52
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Alternative Name
- CD52
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Background
- CD52, also known as CAMPATH-1 antigen, is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein that is tethered to the cell surface with a GPI linkage. This protein can be targeted to induce immune suppression by complement-meditated cell lysis. CD52 is expressed on lymphocytes, monocytes, monocytes-derived dendritic cells, eosinophils, and neutrophils, but not on the stem cells from which these lymphocytes were derived. Also, it is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. Recombinant human CD52, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Molecular Weight
- 28.2 kDa (251aa)
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NCBI Accession
- NP_001794
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UniProt
- P31358
Target
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