DPP4 Protein (AA 39-766) (His tag)
Quick Overview for DPP4 Protein (AA 39-766) (His tag) (ABIN666712)
Target
See all DPP4 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 39-766
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Purification tag / Conjugate
- This DPP4 protein is labelled with His tag.
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Characteristics
- DPP4 (CD26), 39-766aa, Human,His-Tagged, Recombinant, Hi-5 cell
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/ml (determined by Bradford assay)
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Buffer
- Liquid in 20mM Tris-HCl pH 8.0, 100mM NaCl, 1mM EDTA, 10% glycerol
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Storage
- 4 °C
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- DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
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Alternative Name
- DPP4 (CD26)
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Background
- DPP4, dipeptidyl peptidase-4 is a complex enzyme expressed on the surface of most cell types and is a serine exopeptidase that cleaves x-proline dipeptides from the N-terminus of polypeptides. DPP4 protein is associated with intracellular signal transduction, apoptosis and plays an important role in tumor biology. There are at least 63 substrates which can bind specifically to DPP4 enzyme including growth factors, chemokines, neuro peptides. Furthermore, DPP4 plays a major role in glucose metabolism by cleaving incretins such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). Recombinant human DPP4 protein was expressed with c-terminal His-tag in high-5 cells using baculovirus expression system and purified by using conventional chromatography techniques. Synonyms: DPPIV, ADABP, ADCP2, TP103, Dipeptidyl peptidase-4, DPP4, dipeptidyl-peptidase 4, CD26, dipeptidylpeptidase IV (CD26 adenosine deaminase complexing protein 2), adenosine deaminase complexing protein 2,. NCBI no.: NP_001926
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Molecular Weight
- 86.4kDa (746aa), confirmed by MALDI-TOF.
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Pathways
- Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
Target
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