Retinoid X Receptor gamma Protein (AA 111-228)
Quick Overview for Retinoid X Receptor gamma Protein (AA 111-228) (ABIN666801)
Target
See all Retinoid X Receptor gamma (RXRG) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 111-228
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Characteristics
- RXR-alpha( Retinoid x receptor, 111-228aa, Human) Recombinant, expressed in E.coli)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/ml (determined by Bradford assay)
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Buffer
- Liquid. In 20mM Tris-HCl pH7.5, 0.1M NaCl, 5mM beta-Mercaptoethanol
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Storage
- 4 °C
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- Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))
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Alternative Name
- RXR-alpha (Retinoid X Receptor)
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Background
- The retinoid X receptor(RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors(RAR), thyroid hormone receptors(TR), vitamin D receptors and peroxisome proliferators-activated receptors(PPAR). The RXR family includes three difference isoforms, RXR alpha, beta, gamma. Human RXR alpha gene is localized on 9q34.9 and encodes two major isoforms(RXR alpha1, RXR alpha2). The DNA binding domain of RXR(111-228aa) was over expressed in E.coli and purified by using conventional column chromatography techniques. Synonyms: RXRA, NR2B1, RXR-alpha, Retinoid x receptor, Retinoid X receptor alpha, Nuclear receptor subfamily 2 group B member 1, Retinoic acid receptor RXR-alpha, FLJ16020, FLJ16733, MGC102720, Retinoic acid receptor RXR alpha, RXR alpha1, RXRalpha1, RXRA1. NCBI no.: NP_002948
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Molecular Weight
- 13.6 kDa (119 aa), confirmed by MALDI-TOF.
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Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
Target
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