RRAS2 Protein (AA 1-201) (His tag)

Catalog No. ABIN666896

This Recombinant RRAS2 protein is produced in Escherichia coli (E. coli).

Quick Overview for RRAS2 Protein (AA 1-201) (His tag) (ABIN666896)

Target: RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % by SDS - PAGE

Product Details

Protein Characteristics: AA 1-201

Purification tag / Conjugate: This RRAS2 protein is labelled with His tag.

Characteristics: RRAS2, 1- 201 aa, Human, His-tagged, Recombinant, E.coli

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol, 2mM EDTA

Storage: 4 °C

Target Details

Target: RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))

Alternative Name: RRAS2

Background: RAS viral (r-ras) oncogene homolog 2 isoform a, also known as RRAS2, belongs to the Ras like GTPase family that cycle between GTP-bound active and GDP-bound inactive states at the cytoplasmic face of the plasma membrane. It is implicated in the pathogenesis of human cancers. Thus, overexpression of active RRAS2 in EpH4 cells induces tumorigenicity through the phosphoinositide 3-kinase, p38 MAPK, and mTOR pathways, and these cells lose their sensitivity to the normal growth inhibitory role of TGF-beta. Recombinant human RRAS2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TC21, RAS viral (r-ras) oncogene homolog 2 isoform a C86394, Oncogene RRAS2, Oncogene TC21, Ras like protein TC21, Ras related protein R Ras2, Related RAS viral (r ras) oncogene homolog 2, Related RAS viral oncogene homolog 2, RRAS 2, TC 21, Teratocarcinoma oncogene, Teratocarcinoma oncogene TC21. NCBI no.: NP_036382

Molecular Weight: 25.2 kDa (221aa), confirmed by MALDI-TOF.