IVD Protein (AA 33-426) (His tag)

Catalog No. ABIN666949

Recombinant IVD protein expressed in Escherichia coli (E. coli).

Quick Overview for IVD Protein (AA 33-426) (His tag) (ABIN666949)

Target: IVD (Isovaleryl-CoA Dehydrogenase (IVD))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 90 % by SDS - PAGE

Product Details

Protein Characteristics: AA 33-426

Purification tag / Conjugate: This IVD protein is labelled with His tag.

Characteristics: IVD, 33-426aa, Human, His tag, E.coli

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol

Storage: 4 °C

Target Details

Target: IVD (Isovaleryl-CoA Dehydrogenase (IVD))

Alternative Name: IVD

Background: IVD (Isovaleryl Coenzyme A dehydrogenase) is a mitochondrial matrix enzyme that belongs to the acyl-CoA dehydrogenase family. IVD is a homotetrameric flavoenzyme which catalyzes the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA. Defects of the IVD gene lead to ineffective isoforms that are the underlying cause of isovaleric acidemia. Recombinant human IVD protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ACAD2, Isovaleryl-CoA dehydrogenase, mitochondrial Isovaleryl CoA dehydrogenase, Isovaleryl CoA dehydrogenase, mitochondrial, isovaleryl Coenzyme A dehydrogenase. NCBI no.: NP_002216

Molecular Weight: 45.3 kDa (415aa), confirmed by MALDI-TOF.

Pathways: Monocarboxylic Acid Catabolic Process