GLRX3 Protein (AA 1-335) (His tag)
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- Target See all GLRX3 Proteins
- GLRX3 (Glutaredoxin 3 (GLRX3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-335
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GLRX3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- Glutaredoxin-3, 1-335aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT
- Storage
- 4 °C
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- Target
- GLRX3 (Glutaredoxin 3 (GLRX3))
- Alternative Name
- Glutaredoxin-3 (GLRX3 Products)
- Background
- Glutaredoxin(GRX), also known as thioltransferase, is member of the thiol-disulfide oxidoreductase family. Glutraredoxin catalyzes the reversible reduction of protein-glutathionyl mixed disulfides to free sulfhydryl groups though a monothiol mechanism. Glutaredoxin-3 (Grx3/PICOT) is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals. And it has been shown to interact with PRKCQ. Recombinant human Glutaredoxin-3, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Thioredoxin-like protein 2, GLRX3, PICOT, TXNL2, GRX3, glutaredoxin 4, bA500G10.4, GLRX4, GRX4, thioredoxin-like 2, thioredoxin-like 2, glutaredoxin 3,. NCBI no.: NP_006532
- Molecular Weight
- 39.6kDa (355aa), confirmed by MALDI-TOF
- Pathways
- Cell RedoxHomeostasis
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