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GLRX3 Protein (AA 1-335) (His tag)

GLRX3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN666992
  • Target See all GLRX3 Proteins
    GLRX3 (Glutaredoxin 3 (GLRX3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-335
    Origin
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 4
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GLRX3 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    Glutaredoxin-3, 1-335aa, Human, His tag, E.coli
    Purity
    > 95 % by SDS - PAGE
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  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT
    Storage
    4 °C
  • Target
    GLRX3 (Glutaredoxin 3 (GLRX3))
    Alternative Name
    Glutaredoxin-3 (GLRX3 Products)
    Background
    Glutaredoxin(GRX), also known as thioltransferase, is member of the thiol-disulfide oxidoreductase family. Glutraredoxin catalyzes the reversible reduction of protein-glutathionyl mixed disulfides to free sulfhydryl groups though a monothiol mechanism. Glutaredoxin-3 (Grx3/PICOT) is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals. And it has been shown to interact with PRKCQ. Recombinant human Glutaredoxin-3, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Thioredoxin-like protein 2, GLRX3, PICOT, TXNL2, GRX3, glutaredoxin 4, bA500G10.4, GLRX4, GRX4, thioredoxin-like 2, thioredoxin-like 2, glutaredoxin 3,. NCBI no.: NP_006532
    Molecular Weight
    39.6kDa (355aa), confirmed by MALDI-TOF
    Pathways
    Cell RedoxHomeostasis
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