Sonic Hedgehog Protein (SHH) (AA 24-197) (His tag)

Catalog No. ABIN667009

Product Details

Target: Sonic Hedgehog (SHH)

Protein Type: Recombinant

Protein Characteristics: AA 24-197

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Sonic Hedgehog protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: SHH, 24-197aa, Human, His tag, E.coli

Purity: > 95 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl

Storage: 4 °C

Target Details

Target: Sonic Hedgehog (SHH)

Alternative Name: SHH (SHH Products)

Background: SHH, also known as Sonic hedgehog protein, is one of three proteins in the mammalian signaling pathway family called hedgehog. It plays a key role in regulating vertebrate organogenesis, such as in the growth of digits on limbs and organization of the brain. It controls cell division of adult stem cells and has been implicated in development of some cancers. Recombinant human SHH protein, fused to His-tag at C-terminus was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: HHG1, HLP3, HPE3, SMMCI, TPT, TPTPS, Sonic hedgehog protein HHG 1, HLP 3, Holoprosencephaly 3, HPE 3, MCOPCB5, SHH, SMMC I , SMMCI, Sonic Hedgehog (Drosophila) homolog, sonic hedgehog homolog (Drosophila), Sonic hedgehog homolog,. NCBI no.: NP_000184

Molecular Weight: 20.7 kDa (183aa) confirmed by MALDI-TOF

Pathways: Hedgehog Signaling, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development