ICMT Protein (AA 1-227) (His tag)

Catalog No. ABIN667011

This Recombinant ICMT protein is expressed in Escherichia coli (E. coli).

Quick Overview for ICMT Protein (AA 1-227) (His tag) (ABIN667011)

Target: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % by SDS - PAGE

Product Details

Protein Characteristics: AA 1-227

Purification tag / Conjugate: This ICMT protein is labelled with His tag.

Characteristics: PCMT, 1-227aa, Human, His tag, E.coli

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl

Storage: 4 °C

Target Details

Target: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Alternative Name: PCMT

Background: PCMT1, also known as L-isoaspartyl protein carboxyl methyltransferase, is an enzyme that catalyses the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. This protein plays a role in the repair and/or degradation of damaged proteins. Recombinant human PCMT1 protien, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: , Protein-L-isoaspartate O-methyltransferase L isoaspartyl protein carboxyl methyltransferase, L isoaspartyl/D aspartyl methyltransferase, PCMT 1, PIMT, Protein beta aspartate methyltransferase, Protein L isoaspartate (D aspartate) O methyltransferase, Protein L isoaspartyl/D aspartyl methyltransferase,. NCBI no.: AAH08748

Molecular Weight: 28.8 kDa (263aa) confirmed by MALDI-TOF