MYL2 Protein (AA 1-166) (His tag)

Catalog No. ABIN667089

This Recombinant MYL2 protein is expressed in Escherichia coli (E. coli).

Quick Overview for MYL2 Protein (AA 1-166) (His tag) (ABIN667089)

Target: MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % by SDS PAGE

Product Details

Protein Characteristics: AA 1-166

Purification tag / Conjugate: This MYL2 protein is labelled with His tag.

Characteristics: MYL2,1-166 aa, Human, His-tagged, Recombinant, E.coli

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20mM Tris pH 8.0, 20% glycerol, 5mM CaCl2

Storage: 4 °C

Target Details

Target: MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))

Alternative Name: MYL2

Background: Myosin, light chain 2 (MYL2) encodes the regulatory light chain associated with cardiac myosin beta heavy chain. It is an important protein involved in the regulation of myosin ATPase activity in smooth muscle and Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. Recombinant human MYL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: MLC2, CMH10, DKFZp779C0562, Slow cardiac myosin regulatory light chain 2, MYL2, Slow cardiac myosin regulatory light chain 2 Cardiac myosin light chain-2, MLC 2v, MYL 2, Cardiac ventricular myosin light chain 2, RLC of myosin, Myosin light chain 2 regulatory cardiac slow, Myosin light polypeptide 2 regulatory cardiac slow, Myosin regulatory light chain 2 ventricular cardiac muscle isoform, Myosin regulatory light chain 2 ventricular/cardiac muscle isoform, Regulatory light chain of myosin,. NCBI no.: NP_000423

Molecular Weight: 20.9 kDa (186aa), confirmed by MALDI-TOF.

Pathways: Myometrial Relaxation and Contraction