VEGF121 Protein (Isoform 121)

Catalog No. ABIN667096

Recombinant VEGF121 protein expressed in Escherichia coli (E. coli).

Quick Overview for VEGF121 Protein (Isoform 121) (ABIN667096)

Target: VEGF121 (Vascular Endothelial Cell Growth Factor 121 (VEGF121))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % by SDS PAGE

Product Details

Protein Characteristics: Isoform 121

Characteristics: VEGF121, 207-327aa, Human, Recombinant, E.coli

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20 mM Tris-HCl buffer (pH 8.0) containing 10 % glycerol

Storage: 4 °C

Target Details

Target: VEGF121 (Vascular Endothelial Cell Growth Factor 121 (VEGF121))

Alternative Name: VEGF 121

Background: Vascular endothelial growth factor (VEGF) is homodimeric, heparin-binding glycoprotein involved in both angiogenesis and vasculogenesis. VEGF is expressed as multiple alternately spliced isoforms of VEGF121, 165, 189 and 206. VEGF binds to the receptor tyrosine kinases VEGF R1 (Flt-1) and VEGF R2 (KDR/Flk-1) to activate signal transduction and regulate both physiological and pathological angiogenesis. Recombinant VEGF121 protein was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: Vascular endothelial growth factor A isoform f , VPF, VEGF, VEGF-A, Vascular endothelial growth factor A isoform f MVCD1, Vascular endothelial growth factor A, Vascular permeability factor, VEGF A. NCBI no.: NP_001020541

Molecular Weight: 14.2 kDa (122aa), confirmed by MALDI-TOF.